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These problems can be relieved by using medicines like Estriol 1mg/g cream which contain oestrogen. It may take several days or weeks before you notice an improvement. The use of HRT carries risks which need to be considered when deciding whether to start taking it, or whether to carry on taking it. The experience in treating women with a premature menopause (due to ovarian failure or surgery) is limited. If you have a premature menopause the risks of using HRT may be different. Please talk to your doctor. Before you start (or restart) HRT, your doctor will ask about your own and your familys medical history.

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Your doctor may decide to perform a physical examination. This may include an examination of your breasts and/or an internal examination, if necessary. Once you have started on this medicine you should see your doctor for regular check-ups (at least once a year). At these check-ups, discuss with your doctor the benefits and risks of continuing with this medicine. If any of the following applies to you. If you are not sure about any of the points below, talk to your doctor before using this medicine, If any of the above conditions appear for the first time while using this medicine, stop taking it at once and consult your doctor immediately. Tell your doctor if you have ever had any of the following problems, before you start the treatment, as these may return or become worse during treatment with this medicine estriol 50 mcg gel. If so, you should see your doctor more often for check-ups: Tell your doctor if you have Hepatitis C and you are taking the combination drug regimen ombitasvir/paritaprevir/ritonavir, with or without dasabuvir. Taking the combination of these drugs with some oestrogen-containing products may cause increases in liver function blood test results (increase in ALT liver enzyme) the risk of this happening with this medicine is currently unknown. 

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